Pain Killers in Pets: all you need to know about anti-inflammatories


pain killers in pets are crucial inmany conditions to help them remain comfortable in this video I runthrough all you need to know about the most common anti-inflammatories in dogsand cats the non-steroidal anti-inflammatories hi I'm dr.

Alex fromourpetshealth.

Com helping you and your pet to live a healthier happierlife so if you're new to this channel consider subscribing and hitting thatBell notification to make sure you don't miss out on any future videos just likethis one so our non-steroidal anti-inflammatorydrugs which are also known as nonsteroidals and NSAIDs are the mostcommonly prescribed painkiller in dogs and cats they used as pain killers toreduce inflammation and swelling and also to reduce a high temperature nowwhile there are many different options for pain killers in dogs and cats noneof the others have all these effects now the most common use of nonsteroidals indogs and cats is in the management of chronic pain conditions such asarthritis as well as for pain relief following injury or surgery now thesedrugs also have some anti-cancer effects and this is an area of use whereresearch is ongoing and recommendations are changing there are many differentdrugs within the nonsteroidal antiinflammatory class includingcarprofen meloxicam firacoxib and mavacoxib to name but a few these are thensold under many different trade names with the most common or most well-knownmaybe being rimadyl or metacam prevacox and trocoxil again though thereare lots and lots of these so our non-steroidal anti-inflammatories workby stopping the enzymes from working that make pro-inflammatory chemicalsknown as prostaglandins so these prostaglandins cause swelling they causean increase in temperature as well as actually amplifying the pain signalthat's sent to the brain by the local nerves so the enzymes that are blocked areknown as the Cox enzymes specifically cox-1 and cox-2 so Cox one is actuallyresponsible for the function of normal healthy body processes these includemaintaining their intestinal lining and ensuring an adequate blood flow to thekidney blocking cox-1 therefore can result inupsetting normal body functions and so potentially causing the side-effectsthat I'll discuss a little bit later now cox-2 however is the enzyme thatgoes into action whenever damage takes place and so results in the productionof these pro-inflammatory prostaglandins this then results in pain andinflammation so this is important to know because we want to make sure thatwe reduce pain and inflammation but at the same time we want to reduce the riskof side effects in other words we want our drugs to blockCox 2 and not Cox 1 so most readily accessible human NSAIDs do not do thisin dogs and cats and as a result side effects are really common when thesegiven to our pets our pet specific anti-inflammatories however areconsidered cox-2 preferential or cox-1 sparing meaning that they have a muchmore specific action on things that we want while at the same time having lessof effect on normal body function and so reducing the risk of side effects thisis different though between species so an example would be that Rimadyl ismuch more Cox 2 preferential in dogs compared to cats which is why we don'treally use it in cats so this brings us to the potential side effects of thesedrugs now as you can imagine from the way they work the most common sideeffect is mild gastrointestinal upset resulting in diarrhea and vomiting aswell as maybe lethargy and inappetence now this appears to happen in about twoto nine percent of patients probably about five percent on average withreports varying slightly if treatment is continued despite vomiting or diarrheabeing present then there is a risk that this will develop further intointestinal ulceration and this can then progress further into perforation whichobviously can be catastrophic it's also worth noting that the newer drugshaven't consistently been shown to be significantly less likely to produceside effects than our older drugs although certain individuals definitelydo seem to do well on one particular version of a non-steroidal when anotherone did cause side effects so if your dog has had side effects with one thantrying another is very much a sensible idea and this seems to relate very muchto individual rather and specific drug other side effects dohappen although thankfully they are considered rare dogs are more prone toliver damage which occurs in maybe around one in 2,000 patientsand it's generally reversible so long as it is detected early enough and thedamage is not too severe now cats on the other hand are moreprone to kidney damage and while this can happen following a single injectionkidney damage is actually very rare when our non-steroidals are used appropriatelyinterestingly though there are a couple of reports of cats with existing kidneydisease that also had arthritis and that are actually doing better when givenmeloxicam compared to those not treated with this drug an even smallerpercentage of patients will develop clotting problems as these drugs canaffect platelet function and so reduce the ability of the blood to clot so fora full rundown on the safety of these drugs and both cats and dogs then makesure you check out my dedicated videos link below which also then go on todiscuss how to reduce the risks of side effects happening in your pet now one ofthe big ones is to give these drugs with food which may reduce the likelihood ofintestinal upsets and then any patient being given these drugs should bemonitored at home for side effects and if there are any concerns then theyshould be stopped and your vet consulted so as well as vomiting and diarrheasymptoms to look out for include a reduced appetite stopping drinking ordrinking more lethargy weakness yellow or white gums urinating a lot and weightloss as well as looking out for these symptoms it's also advisable for any dogor cat taking non-steroidal anti-inflammatories especially on aregular basis to have blood and urine testing carried out and regularly thiswill vary between patients but a suggested schedule might include apretreatment blood sample another test run two to four weeks later and thenrepeat testing every three to six months or so running these tests may help topick up any liver or kidney damage early and so minimizing the chance of anyserious and significant ongoing side-effects from happening these drugsshould also be used cautiously in patients with pre-existing chronicdisease such as liver disease and kidney disease as well as those patients on anumber of other drugs and these might include things called ACE inhibitorsaspirin steroids and diuretics such as frusemide and also phenobarbital having said thatit can be really difficult in some cases to balance all of the needs of oursenior patients especially those with multiple conditionsI really believe though that where a patient is in chronic pain such as witharthritis it's just not acceptable to ignore this because of a slightincreased risk of side effects so there may be other appropriate drug optionsdepending on your pet but quality of life it should really not be ignored andI discuss this in more more detail in my video on drug treatment and arthritislink below so I hope this helps you better understand this commonly usedclass of drugs if you've got any questions then please leave them belowin the comments I'd love to hear them as always and make sure that you watchthose related videos linked in the description also remember to subscribeand until next time i'm dr.

alex from our pets health because they're family.

Source: Youtube

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